Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Flt4  FMS-like tyrosine kinase 4   (Synonyms: Flt-4, VEGFR3, VEGFR-3)
Results	Reference
1	J:269938 Bovay E, Sabine A, Prat-Luri B, Kim S, Son K, Willrodt AH, Olsson C, Halin C, Kiefer F, Betsholtz C, Jeon NL, Luther SA, Petrova TV, Multiple roles of lymphatic vessels in peripheral lymph node development. J Exp Med. 2018 Nov 5;215(11):2760-2777
1*	J:293098 Jafree DJ, Moulding D, Kolatsi-Joannou M, Perretta Tejedor N, Price KL, Milmoe NJ, Walsh CL, Correra RM, Winyard PJ, Harris PC, Ruhrberg C, Walker-Samuel S, Riley PR, Woolf AS, Scambler PJ, Long DA, Spatiotemporal dynamics and heterogeneity of renal lymphatics in mammalian development and cystic kidney disease. Elife. 2019 Dec 6;8:e48183
1*	J:122404 Kim KE, Sung HK, Koh GY, Lymphatic development in mouse small intestine. Dev Dyn. 2007 Jul;236(7):2020-5
1	J:216439 Lee KM, Danuser R, Stein JV, Graham D, Nibbs RJ, Graham GJ, The chemokine receptors ACKR2 and CCR2 reciprocally regulate lymphatic vessel density. EMBO J. 2014 Nov 3;33(21):2564-80
1	J:244674 Liu X, Pasula S, Song H, Tessneer KL, Dong Y, Hahn S, Yago T, Brophy ML, Chang B, Cai X, Wu H, McManus J, Ichise H, Georgescu C, Wren JD, Griffin C, Xia L, Srinivasan RS, Chen H, Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function. Sci Signal. 2014 Oct 14;7(347):ra97
1	J:241238 Liu X, Uemura A, Fukushima Y, Yoshida Y, Hirashima M, Semaphorin 3G Provides a Repulsive Guidance Cue to Lymphatic Endothelial Cells via Neuropilin-2/PlexinD1. Cell Rep. 2016 Nov 22;17(9):2299-2311
1	J:262023 Morooka N, Futaki S, Sato-Nishiuchi R, Nishino M, Totani Y, Shimono C, Nakano I, Nakajima H, Mochizuki N, Sekiguchi K, Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling. Circ Res. 2017 Apr 14;120(8):1276-1288
1	J:149138 Norrmen C, Ivanov KI, Cheng J, Zangger N, Delorenzi M, Jaquet M, Miura N, Puolakkainen P, Horsley V, Hu J, Augustin HG, Yla-Herttuala S, Alitalo K, Petrova TV, FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1. J Cell Biol. 2009 May 4;185(3):439-57
1	J:254421 Otowa Y, Moriwaki K, Sano K, Shirakabe M, Yonemura S, Shibuya M, Rossant J, Suda T, Kakeji Y, Hirashima M, Flt1/VEGFR1 heterozygosity causes transient embryonic edema. Sci Rep. 2016 Jun 2;6:27186
1	J:158668 Qu X, Tompkins K, Batts LE, Puri M, Baldwin S, Abnormal embryonic lymphatic vessel development in Tie1 hypomorphic mice. Development. 2010 Apr;137(8):1285-95
1*	J:217439 Srinivasan RS, Escobedo N, Yang Y, Interiano A, Dillard ME, Finkelstein D, Mukatira S, Gil HJ, Nurmi H, Alitalo K, Oliver G, The Prox1-Vegfr3 feedback loop maintains the identity and the number of lymphatic endothelial cell progenitors. Genes Dev. 2014 Oct 1;28(19):2175-87
1	J:237534 Wang Y, Baeyens N, Corti F, Tanaka K, Fang JS, Zhang J, Jin Y, Coon B, Hirschi KK, Schwartz MA, Simons M, Syndecan 4 controls lymphatic vasculature remodeling during mouse embryonic development. Development. 2016 Dec 01;143(23):4441-4451
1	J:177405 Zhang L, Zhou F, Han W, Shen B, Luo J, Shibuya M, He Y, VEGFR-3 ligand-binding and kinase activity are required for lymphangiogenesis but not for angiogenesis. Cell Res. 2010 Dec;20(12):1319-31